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Active Caspase-3 mouse mAb(5E1)

簡要描述：SourceMouseApplicationsIF

  • 產品型號：
  • 廠商性質：生產廠家
  • 更新時間：2025-07-28
  • 訪  問  量：192

詳細介紹

  • Source

    Mouse

  • Applications

    IF,WB,IHC

  • Reactivity

    Human,Mouse,Rat,Chicken

  • Dilution

    IF: 1:50-200 WB: 1:500-1000 IHC: 1:100-200

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Active Caspase-3 protein.

  • Source/Purification

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Recombinant Protein of Active Caspase-3

  • Uniprot No

    P42574

  • Alternative names

    CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1

  • Form

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • Clonality

    Monoclonal

  • Isotype

    IgG

  • Background

    caspase 3(CASP3) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],

  • Other

    CASP3, Caspase-3; Protein Yama; SREBP cleavage activity 1; SCA-1

  • Concentration

    1 mg/ml

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