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Adducin β rabbit pAb

簡要描述：SourceRabbitApplicationsWB,IF,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000

  • 產品型號：
  • 廠商性質：生產廠家
  • 更新時間：2025-07-28
  • 訪  問  量：176

詳細介紹

  • Source

    Rabbit

  • Applications

    WB,IF,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Adducin β Polyclonal Antibody detects endogenous levels of Adducin β protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human ADD2. AA range:471-520

  • Uniprot No

    P35612

  • Alternative names

    ADD2; ADDB; Beta-adducin; Erythrocyte adducin subunit beta

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    adducin 2(ADD2) Homo sapiens Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region i

  • Other

    ADD2, Beta-adducin

  • Mol.Wt (Da)

    80854

  • Concentration

    1 mg/ml

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