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AKAP 250 rabbit pAb

簡要描述：SourceRabbitApplicationsIHC,IF,ELISAReactivityHumanDilutionIHC:1:100-1:300

  • 產品型號：
  • 廠商性質：生產廠家
  • 更新時間：2025-07-28
  • 訪  問  量：205

詳細介紹

  • Source

    Rabbit

  • Applications

    IHC,IF,ELISA

  • Reactivity

    Human

  • Dilution

    IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    AKAP 250 Polyclonal Antibody detects endogenous levels of AKAP 250 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human AKAP12. AA range:301-350

  • Uniprot No

    Q02952

  • Alternative names

    AKAP12; AKAP250; A-kinase anchor protein 12; AKAP-12; A-kinase anchor protein 250 kDa; AKAP 250; Gravin; Myasthenia gravis autoantigen

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    A-kinase anchoring protein 12(AKAP12) Homo sapiens The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

  • Other

    AKAP12, A-kinase anchor protein 12

  • Mol.Wt (Da)

    191483

  • Concentration

    1 mg/ml

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