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Alix rabbit pAb

簡要描述：SourceRabbitApplicationsWB

  • 產品型號：
  • 廠商性質：生產廠家
  • 更新時間：2025-10-15
  • 訪  問  量：169

詳細介紹

  • Source

    Rabbit

  • Applications

    WB, ELISA

  • Reactivity

    Human

  • Dilution

    WB 1:500-2000, ELISA(peptide)1:5000-20000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of human Alix

  • Source/Purification

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized peptide derived from human Alix

  • Uniprot No

    Q8WUM4

  • Alternative names

    Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (Hp95)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    programmed cell death 6 interacting protein(PDCD6IP) Homo sapiens This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012],

  • Other

    PDCD6IP AIP1 ALIX KIAA1375, Alix

  • Concentration

    1 mg/ml

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