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當(dāng)前位置：首頁(yè)   >  產(chǎn)品中心  >    /  Primary Antibodies  /  ALK (phospho-Tyr1278/1282/1283) rabbit pAb

ALK (phospho-Tyr1278/1282/1283) rabbit pAb

簡(jiǎn)要描述：

  • 產(chǎn)品型號(hào)：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時(shí)間：2025-10-15
  • 訪  問  量：154

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human

  • Dilution

    WB 1:1000-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of Human ALK (phospho-Tyr1278 or 1282 or 1283)

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized phosho peptide around human ALK (Tyr1278 and 1282 and 1283)

  • Uniprot No

    Q9UM73

  • Alternative names

    ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    anaplastic lymphoma receptor tyrosine kinase(ALK) Homo sapiens This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome

  • Other

    ALK, ALK (Tyr1278/1282/1283)

  • Concentration

    1 mg/ml

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