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Catenin-β mouse mAb(4F2)

簡要描述：SourceMouseApplicationsWB

  • 產品型號：
  • 廠商性質：生產廠家
  • 更新時間：2025-07-27
  • 訪  問  量：211

詳細介紹

  • Source

    Mouse

  • Applications

    WB,IF,IHC

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:1000-2000 IHC: 1:200-500 IF 1:200

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous Catenin-β protein.

  • Source/Purification

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Recombinant Protein of Catenin-β

  • Uniprot No

    P35222

  • Alternative names

    CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin

  • Form

    PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

  • Clonality

    Monoclonal

  • Isotype

    IgG

  • Background

    catenin beta 1(CTNNB1) Homo sapiens The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],

  • Other

    CTNNB1, Catenin beta-1

  • Concentration

    1 mg/ml

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